Revue : Antimicrobial Agents and Chemotherapy

High prevalence of SXT/R391-related integrative and conjugative elements carrying blaCMY-2 in Proteus mirabilis from gull isolates in the South of France

Auteurs :

Aberkane S., Compain F., Decré D., Dupont C., Laurens C., Vittecoq M., Pantel A., Solassol J., Carrière C., Renaud F., Brieu N., Lavigne J.-P., Bouzinbi N., Ouédraogo A.-S., Jean-Pierre H., Godreuil S.

* Auteur correspondant : Salim Aberkane (e-mail)

Résumé :

The genetic structures involved in the dissemination of bla CMY-2 carried by Proteus mirabilis isolates recovered from different gull species in the South of France were characterized and compared to clinical isolates. blaCMY-2  was identified in P. mirabilis isolates from 27/93 yellow-legged gulls and 37/65 slender-billed gulls. It was carried by a conjugative SXT/R391-like ICE in all avian strains and in 3/7 human strains. Two clinical isolates had the same genetic background as six avian isolates.

Référence bibliographique complète :

Aberkane S., Compain F., Decré D., Dupont C., Laurens C., Vittecoq M., Pantel A., Solassol J., Carrière C., Renaud F., Brieu N., Lavigne J.-P., Bouzinbi N., Ouédraogo A.-S., Jean-Pierre H., Godreuil S. 2015. High prevalence of SXT/R391-related integrative and conjugative elements carrying blaCMY-2 in Proteus mirabilis from gull isolates in the South of France. Antimicrobial Agents and Chemotherapy. Doi :10.1128/AAC.01654-15